Mouse model of the human serotonin transporter-linked polymorphic region
نویسندگان
چکیده
منابع مشابه
association between the serotonin- transporter- linked polymorphic region (5-httlpr) and pemphigous disease in iranian patients
introduction : pemphigus vulgaris (pv) is a relatively rare autoimmune disease characterized by blistering of the skin and mucosa. the main objective of this study was to investigate the possible association between the 5-httlpr polymorphism and pv in iranian patients. for this, 112 pv and 100 controls were enrolled in this study. materials and methods : in this case-control study, genomic dna ...
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Some allelic variants of the serotonin transporter linked polymorphic region (5-HTTLPR) result in lower levels of expression of the serotonin transporter gene (SLC6A4). These low-expressing (LE) alleles are associated with mental-health disorders in a minority of humans that carry them. Humans are not the only primates that exhibit this polymorphism; other species, including some monkeys, also ...
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Early-onset methamphetamine use increases the lifetime prevalence of methamphetamine dependence. An earlier onset of methamphetamine use leads to greater damage to the terminal ends of serotonin neurons, more reduction in serotonin transporter (5-HTT) density, and an increased propensity toward further methamphetamine use. Because the 5-HTT-linked polymorphic region (5'-HTTLPR) within the promo...
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Risky decision making is a complex process that involves weighing the probabilities of alternative options that can be desirable, undesirable, or neutral. Individuals vary greatly in how they make decisions either under ambiguity and/or under risk. Such individual differences may have genetic bases. Based on previous studies on the genetic basis of decision making, two decision making tasks [i....
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ژورنال
عنوان ژورنال: Mammalian Genome
سال: 2019
ISSN: 0938-8990,1432-1777
DOI: 10.1007/s00335-019-09815-2